LOXL3 Antibody | F42503-0.4ML

LOXL3 Antibody | F42503-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This LOXL3 antibody is available for research use only.

Purity: Antigen affinity

Description: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.

Immunogen: A portion of amino acids 715-744 from the human protein was used as the immunogen for this LOXL3 antibody.

Storage: Aliquot the LOXL3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.