Description
LMNB1 Polyclonal Antibody | E-AB-18237 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC, ELISA
Research Area: Cancer, Cell Biology, Signal Transduction, Tags and Cell Markers
Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Lead Time: 7~10 days
Concentration: 0.5 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human LMNB1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:2000-1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: 67 kDa
Observed Molecular Weight: Refer to figures
Clonality: Polyclonal
