Description
LKB1 Antibody | R31683 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This LKB1 antibody is available for research use only.
Purity: Antigen affinity
Description: Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor. STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
Immunogen: Human partial recombinant protein (AA 62-430) was used as the immunogen for this LKB1 antibody.
Storage: The lyophilized LKB1 antibody can be stored at 4oC to -20 °C. After reconstitution, aliquot and store at -20 °C. Avoid repeated freeze/thaws.