LKB1 Antibody (Liver Kinase B1) | F50223-0.08ML

LKB1 Antibody (Liver Kinase B1) | F50223-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, IF, ELISA

Buffer: N/A

Limitation: This LKB1 antibody is available for research use only.

Purity: Purified

Description: LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. [UniProt]

Immunogen: A portion of amino acids 19-48 from the human protein was used as the immunogen for this LKB1 antibody.

Storage: Aliquot the LKB1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.