LEF1 Antibody / Lymphoid enhancer-binding factor 1 / TCF1 alpha | RQ6490

LEF1 Antibody / Lymphoid enhancer-binding factor 1 / TCF1 alpha | RQ6490 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, IF, FACS, Direct ELISA

Buffer: Lyophilized from 1X PBS with 2% Trehalose

Limitation: This TCF1 alpha antibody is available for research use only.

Purity: Affinity purified

Description: Lymphoid enhancer-binding factor 1 (LEF1), also called T cell-specific transcription factor 1-alpha (TCF1 alpha) is a protein that in humans is encoded by the LEF1 gene. This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Immunogen: An E. coli-derived human protein (amino acids D14-H274) was used as the immunogen for the TCF1 alpha antibody.

Storage: After reconstitution, the TCF1 alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.