LEF1 Antibody | F53737-0.1ML

LEF1 Antibody | F53737-0.1ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In ascites with 0.09% sodium azide

Format: Ascites

Clone: 661CT8.3.5

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This LEF1 antibody is available for research use only.

Purity: Ascites

Description: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Immunogen: A portion of amino acids 10-37 from the human protein was used as the immunogen for this LEF1 antibody.

Storage: Aliquot the LEF1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.