Description
LDLR Antibody | F51451-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, FACS, ELISA
Buffer: N/A
Limitation: This LDLR antibody is available for research use only.
Purity: Antigen affinity
Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
Immunogen: A portion of amino acids 391-419 from the human protein was used as the immunogen for this LDLR antibody.
Storage: Aliquot the LDLR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
