LDLR Antibody | F51451-0.4ML

LDLR Antibody | F51451-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, FACS, ELISA

Buffer: N/A

Limitation: This LDLR antibody is available for research use only.

Purity: Antigen affinity

Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.

Immunogen: A portion of amino acids 391-419 from the human protein was used as the immunogen for this LDLR antibody.

Storage: Aliquot the LDLR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.