Description
LCK Antibody | F50711-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: IHC, IF, FACS, WB, ELISA
Buffer: N/A
Limitation: This LCK antibody is available for research use only.
Purity: Antigen affinity
Description: LSK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LSK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t(1;7)(p34;q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.
Immunogen: A portion of amino acids 23-52 from the human protein was used as the immunogen for this LCK antibody.
Storage: Aliquot the LCK antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
