Description
LCK Antibody | F48246-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, FACS, WB, ELISA
Buffer: N/A
Limitation: This LCK antibody is available for research use only.
Purity: Purified
Description: LCK is a member of the Src family of protein tyrosine kinases (PTKs). This protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
Immunogen: A portion of amino acids 480-509 from the human protein was used as the immunogen for this LCK antibody.
Storage: Aliquot the LCK antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
