LCK Antibody | F48246-0.08ML

LCK Antibody | F48246-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, FACS, WB, ELISA

Buffer: N/A

Limitation: This LCK antibody is available for research use only.

Purity: Purified

Description: LCK is a member of the Src family of protein tyrosine kinases (PTKs). This protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.

Immunogen: A portion of amino acids 480-509 from the human protein was used as the immunogen for this LCK antibody.

Storage: Aliquot the LCK antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.