LATS2 Antibody | F40138-0.4ML

LATS2 Antibody | F40138-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This LATS2 antibody is available for research use only.

Purity: Purified

Description: LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Immunogen: A portion of amino acids 228-258 from the human protein was used as the immunogen for this LATS2 antibody.

Storage: Aliquot the LATS2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.