LAQ824 (NVP-LAQ824,Dacinostat) | 27760-2

LAQ824 (NVP-LAQ824,Dacinostat) | 27760-2 | Gentaur US, UK & Europe Disrtribition

Category: Deacetylase/Inhibitors / Activators

Application: N/A

Background: A recent study shows that LAQ824 induces chromatin changes at the level of the IL-10 gene promoter that lead to enhanced recruitment of the transcriptional repressors HDAC11 and PU.1 and inhibits IL-10 production in BALB/c murine macrophages.

Description: LAQ824 (also known as NVP-LAQ824 or Dacinostat), a derivative of 4-aminomethylcinnamic hydroxamic acid, is a novel and potent inhibitor of histone deacetylase (HDAC) that inhibits the activity of HDAC with IC50 value of 0.03 µM.

Product Type: Inhibitor

Shippement Condition: Room temp. (continental US) or gel packs