Lambda Light Chain Antibody | V8873-100UG

Lambda Light Chain Antibody | V8873-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: LLC/3774R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the recombinant Lambda Light Chain antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Immunogen: Recombinant full-length human IGL protein was used as the immunogen for the recombinant Lambda Light Chain antibody.

Storage: Aliquot the recombinant Lambda Light Chain antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cell Surface, cytoplasmic and secreted