Lambda Light Chain Antibody / Lambda Antibody | V3151-20UG

Lambda Light Chain Antibody / Lambda Antibody | V3151-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: HP6054

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, WB, IHC-P

Buffer: N/A

Limitation: This Lambda Light Chain antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Immunogen: Purified human IgG myeloma proteins were used as the immunogen for this Lambda Light Chain antibody.

Storage: Store the Lambda Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).