Lambda Light Chain Antibody Cocktail | V2155SAF-100UG

Lambda Light Chain Antibody Cocktail | V2155SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: LcN-2 + ICO-106

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, WB

Buffer: N/A

Limitation: This Lambda Light Chain antibody cocktail is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody cocktail is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Lambda light chain antibody is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Immunogen: Purified human Ig (LcN-2 and ICO-106) was used as the immunogen for this Lambda Light Chain antibody cocktail.

Storage: Store the Lambda Light Chain antibody cocktail at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).