Description
Ku80 Antibody / XRCC5 | RQ5399 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: FAE-24
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This Ku80 antibody is available for research use only.
Purity: Affinity purified
Description: The protein encoded by the XRCC5 gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [RefSeq]
Immunogen: A synthetic peptide specific to human Ku80 / XRCC5 was used as the immunogen for the Ku80 antibody.
Storage: Store the Ku80 antibody at -20 °C.
