Description
Ku70 + Ku80 Antibody | V2128CF488-100T | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: CF488 Conjugate
Clone: KU729
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF
Buffer: N/A
Limitation: This Ku70 + Ku80 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Immunogen: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
Storage: Store the Ku70 + Ku80 antibody at 2-8oC, protected from light.
