Description
KLF4 Antibody | F48145-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IF, IHC, ELISA
Buffer: N/A
Limitation: This KLF4 antibody is available for research use only.
Purity: Purified
Description: Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development Contributes to the down-regulation of p53/TP53 transcription.
Immunogen: A portion of amino acids 69-101 from the human protein was used as the immunogen for this KLF4 antibody.
Storage: Store at 4oC for up to one month. For long term, aliquot the KLF4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
