Description
Kindlin-3 Antibody / URP2 / FERMT3 | F53966-0.2ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Mouse
Application: WB
Buffer: N/A
Limitation: This Kindlin-3 antibody is available for research use only.
Purity: Antigen affinity
Description: Fermitin family homolog 3, also called Kindlin-3, plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).
Immunogen: A portion of amino acids 117-151 from the mouse protein was used as the immunogen for the Kindlin-3 antibody.
Storage: Aliquot the Kindlin-3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.