Description
Ki67 Antibody | V3871SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: PMKI67-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P, FACS, IF
Buffer: N/A
Limitation: This Ki67 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. [UniProt]
Immunogen: A portion of amino acids 2293-2478 was used as the immunogen for the Ki67 antibody.
Storage: Store the Ki67 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
