Ki67 Antibody | V3871-20UG

Ki67 Antibody | V3871-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: PMKI67-1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P, FACS, IF

Buffer: N/A

Limitation: This Ki67 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. [UniProt]

Immunogen: A portion of amino acids 2293-2478 was used as the immunogen for the Ki67 antibody.

Storage: Store the Ki67 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).