Description
Ki-67 Antibody | V3866BTN | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Biotin Conjugate
Clone: MKI67/2465
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF, IHC-P
Buffer: N/A
Limitation: This Ki-67 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.
Immunogen: A portion of amino acids 2293-2478 from the human protein was used as the immunogen for the Ki-67 antibody.
Storage: Store the Ki-67 antibody at 2-8oC (up to one month) or aliquot and store at -20 °C (longer term).
