Description
KDM6A Antibody | F53253-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This KDM6A antibody is available for research use only.
Purity: Antigen affinity
Description: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Immunogen: This KDM6A antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 797-832 amino acids from the Central region of human KDM6A.
Storage: Aliquot the KDM6A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
