Kappa Light Chain Antibody | V3846SAF-100UG

Kappa Light Chain Antibody | V3846SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: rKLC709

Host: Mouse

Clonality: Recombinant Mouse Monoclonal

Isotype: Mouse IgG1, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Application Note: The optimal dilution of the recombinant anti-Kappa light chain antibody for each application should be determined by the researcher.

Purity: Protein G affinity chromatography

Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Immunogen: Recombinant human Ig kappa chain was used as the immunogen for this recombinant anti-Kappa light chain antibody.

Storage: Store the recombinant anti-Kappa light chain antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

Localization: Cell Surface, cytoplasmic and secreted