Description
Kappa Light Chain Antibody | V3846-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: rKLC709
Host: Mouse
Clonality: Recombinant Mouse Monoclonal
Isotype: Mouse IgG1, kappa
Species Reactivity: Human
Application: IHC-P
Application Details: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note: The optimal dilution of the recombinant anti-Kappa light chain antibody for each application should be determined by the researcher.
Purity: Protein G affinity chromatography
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Immunogen: Recombinant human Ig kappa chain was used as the immunogen for this recombinant anti-Kappa light chain antibody.
Storage: Store the recombinant anti-Kappa light chain antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
Localization: Cell Surface, cytoplasmic and secreted
