Description
Kallikrein-5 Antibody | R30713 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Mouse, Rat
Application: WB, IHC-P
Buffer: N/A
Limitation: This Kallikrein-5 antibody is available for research use only.
Purity: Antigen affinity
Description: Kallikrein-5, formerly known as Stratum corneum tryptic enzyme (SCTE) or KLKL2, is a serine protease expressed in the epidermis. The gene is one of the fifteen kallikrein subfamily members which is located on 19q13.41. KLK5 has been suggested to regulate cell shedding in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. The KLK5 gene contains 5 coding exons spanning 9.3. KLK5 expression is upregulated in a breast cancer cell line in the presence of estrogens and progestins and is associated with more aggressive forms of epithelial ovarian carcinoma.
Immunogen: An amino acid sequence from the C-terminus of mouse Kallikrein-5 (NLCEFVKWIKDTMNSN) was used as the immunogen for this Kallikrein-5 antibody.
Storage: After reconstitution, the Kallikrein-5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
