Description
Kaempferol | 27757 | Gentaur US, UK & Europe Disrtribition
Category: Deacetylase/Inhibitors / Activators
Application: N/A
Background: N/A
Description: Naturally occurring flavonoid found in Gingko biloba and red wines that activates the mitochondrial Ca2+ uniporter (EC50 = 7 µM). Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Pan-HDAC inhibitor; in vitro profiling of all conserved human HDACs of class I, II and IV showed that kaempferol inhibited all tested HDACs.
Product Type: Inhibitor
Shippement Condition: Room temp. (continental US) or gel packs
