JNK3 Antibody (MAPK10) | F50466-0.08ML

JNK3 Antibody (MAPK10) | F50466-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This JNK3 antibody is available for research use only.

Purity: Purified

Description: JNK3 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this JNK3 antibody.

Storage: Aliquot the JNK3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.