Description
JMJD2E (KDM4DL) Homogeneous Assay Kit | 50417 | Gentaur US, UK & Europe Disrtribition
Category: Demethylase/Assay Kit
Application: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: JMJD2E, also known as KDM4DL (lysine (K)-specific demethylase 4D-like) is a JmjC-domain protein that exhibits demethylation activity toward H3-K9Me3 and H3-K36Me3.
Description: The JMJD2E Homogeneous Assay Kit is designed to measure activity of JMJD2E for screening and profiling applications, using AlphaLISA® technology. The key to the JMJD2E Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing JMJD2E enzyme is incubated with the biotinylated substrate for two hours. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alphacounts.
Product Type: Assay Kit
Shippement Condition: -80°C
