Description
JMJD2D (KDM4D) Chemiluminescent Assay Kit | 50418 | Gentaur US, UK & Europe Disrtribition
Category: Demethylase/Assay Kit
Application: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: JMJD2D is a JmjC-domain protein that exhibits demethylation activity toward H3-K9Me3 and H3-K9Me2.
Description: The JMJD2D Chemiluminescent Kit is designed to measure activity of JMJD2D for screening and profiling applications. The key to the JMJD2D Chemiluminescent Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing JMJD2D enzyme is incubated with a sample containing assay buffer for one hour. Next, primary antibody is added. Finally, the plate is treated with an HRP-labeled secondary antibody followed by addition of the HRP substrate to produce chemiluminescence that can then be measured using a chemiluminescence reader.
Product Type: Assay Kit
Shippement Condition: -80°C