Description
JMJD2B Homogeneous Assay Kit | 50414-1 | Gentaur US, UK & Europe Disrtribition
Category: Demethylase/Assay Kit
Application: Great for studying enzyme kinetics and HTS applications.
Background: N/A
Description: The JMJD2B Homogeneous Assay Kit is designed to measure JMJD2B activity for screening and profiling applications. JMJD2B, also known as JHDM3B and KDM4B, is a JumonjiC (JmjC) domain containing histone lysine demethylase that exhibits demethylation activity toward H3-K9Me3 and H3-K36Me3. The key to the JMJD2B Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing JMJD2B enzyme is incubated with the biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.
Product Type: Assay Kit
Shippement Condition: -80°C