JIP1 Antibody / MAPK8IP1 | F55015-0.08ML

JIP1 Antibody / MAPK8IP1 | F55015-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IF, FACS, IHC-P, WB

Buffer: N/A

Limitation: This MAPK8IP1 antibody is available for research use only.

Purity: Antigen affinity purified

Description: JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.

Immunogen: A portion of amino acids 470-498 from the human protein was used as the immunogen for the MAPK8IP1 antibody.

Storage: Aliquot the MAPK8IP1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.