JHDM1D Antibody / KDM7A | F54415-0.4ML

JHDM1D Antibody / KDM7A | F54415-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: FACS, IHC-P, WB

Buffer: N/A

Limitation: This JHDM1D antibody is available for research use only.

Purity: Antigen affinity purified

Description: JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.

Immunogen: A portion of amino acids 290-316 from the human protein was used as the immunogen for the JHDM1D antibody.

Storage: Aliquot the JHDM1D antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.