ITGA2B Polyclonal Antibody | E-AB-61058

ITGA2B Polyclonal Antibody | E-AB-61058 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, IF

Research Area: Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells

Background: This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human ITGA2B (NP_000410.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:10-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 103 kDa/109 kDa/113 kDa

Observed Molecular Weight: 135 kDa

Clonality: N/A