IRF4 Antibody (MUM1) | R31635

IRF4 Antibody (MUM1) | R31635 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This IRF4 antibody is available for research use only.

Purity: Antigen affinity

Description: Interferon regulatory factor 4, also known as MUM1, is a protein that in humans is encoded by the IRF4 gene. It is located on 6p25.3. IRF4 is a transcription factor, and it is essential for the development of T helper-2 (Th2) cells, IL17 -producing Th17 cells, and IL9 -producing Th9 cells. In melanocytic cells, the gene may be regulated by MITF. IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation, sensitivity of skin to sun exposure, freckles, blue eyes, and brown hair color. Additionally, IRF4 inhibition is toxic to myeloma cell lines, regardless of transforming oncogenic mechanism.

Immunogen: Human partial recombinant protein (AA 272-451) was used as the immunogen for this IRF4 antibody.

Storage: After reconstitution, the IRF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.