IRF1 Antibody | RQ5339

IRF1 Antibody | RQ5339 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: DHE-9

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human, Rat

Application: IHC-P, WB

Buffer: N/A

Limitation: This IRF1 antibody is available for research use only.

Purity: Affinity purified

Description: The protein encoded by the IRF1 gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [RefSeq]

Immunogen: A synthetic peptide specific to human Interferon regulatory factor 1 was used as the immunogen for the IRF1 antibody.

Storage: Store the IRF1 antibody at -20 °C.