Description
Irak1 Antibody | F43845-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Mouse
Application: WB, FACS, ELISA
Buffer: N/A
Limitation: This Irak1 antibody is available for research use only.
Purity: Antigen affinity
Description: Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.
Immunogen: A portion of amino acids 405-433 from the mouse protein was used as the immunogen for this Irak1 antibody.
Storage: Aliquot the Irak1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
