Interferon alpha 1 Antibody / IFNA1 | V7854-20UG

Interferon alpha 1 Antibody / IFNA1 | V7854-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: 2.48

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, WB, IHC-F, IF

Buffer: N/A

Limitation: This IFNA1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Immunogen: Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.

Storage: Store the IFNA1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).