Integrin alpha E Antibody / CD103 | V3837-100UG

Integrin alpha E Antibody / CD103 | V3837-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: ITGAE/2474

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This CD103 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E-beta-7 integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. This antibody is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).

Immunogen: A portion of amino acids 775-855 from the human protein was used as the immunogen for the CD103 antibody.

Storage: Store the CD103 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).