Integrin alpha 4 Antibody / ITGA4 | RQ5406

Integrin alpha 4 Antibody / ITGA4 | RQ5406 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: IHH-9

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This ITGA4 antibody is available for research use only.

Purity: Affinity purified

Description: The ITGA4 gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [RefSeq]

Immunogen: A synthetic peptide specific to human Integrin alpha 4 / ITGA4 was used as the immunogen for the ITGA4 antibody.

Storage: Store the ITGA4 antibody at -20 °C.