Insulin Receptor Antibody / INSR | RQ5135

Insulin Receptor Antibody / INSR | RQ5135 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: GGA-9

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This Insulin Receptor antibody is available for research use only.

Purity: Affinity purified

Description: The INSR gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [RefSeq]

Immunogen: A synthetic peptide specific to human Insulin Receptor / INSR was used as the immunogen for the Insulin Receptor antibody.

Storage: Store the Insulin Receptor antibody at -20 °C.