Description
Insulin Polyclonal Antibody | E-AB-70202 | Gentaur US, UK & Europe Disrtribition
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Application: IHC
Research Area: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction
Background: Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.
Lead Time: 7~10 days
Concentration: 300 μg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein corresponding to Mouse insulin
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: IHC 1:200-1:1000
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: N/A
Clonality: Polyclonal