Description
Insulin Antibody | F53596-0.1ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In ascites with 0.09% sodium azide
Format: Ascites
Clone: 396CT20.4.4
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This Insulin antibody is available for research use only.
Purity: Ascites
Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Immunogen: A portion of amino acids 35-64 from the human protein was used as the immunogen for this Insulin antibody.
Storage: Aliquot the Insulin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
