Description
INSM2 Antibody / Insulinoma Associated 2 | V8752-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: INSM2/4291
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This INSM2 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.
Immunogen: A portion of amino acids 432-540 from the human protein was used as the immunogen for the INSM2 antibody.
Storage: Store the INSM2 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
