Inhibitor

Milrinone | 27309 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: PDE InhibitorOur Inhibitors are extremely Pure Product Type: Inhibitor Shippement...

GSK256066 | 27751-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: GSK256066 is a selective PDE4 inhibitor with an exceptionally high-affinity and...

Pimobendan | 27638-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 µM. Product Type: ...

Apremilast (CC-10004) | 27735-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Apremilast, also known as CC-10004, is a novel and potent small-molecule...

RGFP966 | 27643-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: RGFP966 is a slow-on/slow-off, competitive tight-binding HDAC inhibitor. RGFP966 treatment on two CTCL cell...

PCI 34051 | 27317 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Caspase and HDAC Inhibitor Product Type: Inhibitor Shippement Condition: room temp or...

KY 02111 | 27759-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: N/A Description: Promotes differentiation of human ESCs and iPSCs into cardiomyocytes. Induces downregulation of...

BMN-673 8R,9S | 27610-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with...

LAQ824 (NVP-LAQ824,Dacinostat) | 27760-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: A recent study shows that LAQ824 induces chromatin changes at the level of the IL-10 gene...

ICG 001 | 27752-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: ICG001 selectively inhibits colon carcinoma cell lines (SW480 and HCT-116 cells) but not normal colonic epithelial...

EPZ5676 | 27625-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ5676 is a potent inhibitor of DOT1L histone methyltransferase that, according to X-ray crystallographic...

AR-42 (OSU-HDAC42) | 27603-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: AR-42 induces histone H3 acetylation, α-tubulin acetylation and p21 up-regulation, which have been...

A-966492 | 27601-3 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: A-966492 is one of the most potent PARP inhibitors. A-966492 displays excellent potency against the PARP-1 enzyme with...

CUDC-907 | 27616-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: CUDC-907 has a long half-life in murine tumors. CUDC-907 induces apoptosis and inhibits cancer cell...

BMN 673 | 27609-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: BMN673 has shown anti-tumor activity both in vitro and in vivo. It inhibited proliferation of tumor cells and...

Pracinostat (SB939) | 27771-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor...

Caspase-3/7 Inhibitor I | 27741-3 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Selectivity for caspases-3 and 7 involves unique hydrophobic residues in the S2 pocket surrounding the catalytic...

(-)-JQ1 | 27335 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: (-)-JQ1 is the inactive stereoisomer of the potent, cell-permeable, small molecule bromodomain inhibitor (+)-JQ1...

CHIR-99021 (CT99021) HCl | 27615-3 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: Hydrochloride salt of CHIR 99021, a highly selective glycogen synthase kinase-3...

CHIR-99021 (CT99021) | 27614-3 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: CHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor that can...

Trimidox | 27320 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis/Inhibitors & Activators Application: N/A Background: N/A Description: Caspase Activator Product Type: Inhibitor Shippement Condition: room temp.

Wnt-C59 | 27780-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: Wnt-C59 prevents palmitoylation of Wnt proteins by Porcupine (a membrane-bound O-acyltransferase), thereby blocking...

Z-VEID-FMK | 27669-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VEID is the specific recognition sequence for caspase-6/Mch2. Caspase 6 is only one of at least three effector caspases, the...

Z-VDVAD-FMK | 27668-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VDVAD has been shown to be a preferred cleavage site for caspase-2. Caspase 2 is a very versatile caspase with multiple...

3-Deazaneplanocin A (DZNep) hydrochloride | 27618-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: 3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase...

3-Deazaneplanocin (DZNep) | 27617-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: 3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase inhibitor and histone...

Boc-D-FMK | 27611-3 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Boc-D-FMK is a cell-permeable broad-spectrum caspase inhibitor that fully inhibits the pro-apoptotic effect of tumor necrosis...

OTX-015 | 27636-3 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites, including...

Oxyresveratrol | 27318 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis/Inhibitors & Activators Application: N/A Background: N/A Description: Caspase-3 Inhibitor Product Type: Inhibitor Shippement Condition: room temp or gel...

Tenovin-6 | 27661-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Tenovin-6 is the water soluble analog of Tenovin-1 and acts as a potent SIRT1 and SIRT2...

Cilomilast | 27742-3 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Cilomilast, also known as SB-207499 or Ariflo, is a potent second generation...

TCID | 27720-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for cell-based and in vitro studies of UCH-L3 function. Background: N/A Description: A potent and selective inhibitor...

Tadalafil | 27657-3 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Tadalafil is a small-molecule inhibitor of phosphodiesterase 5 (PDE5), a predominant PDE in the...

SGC-CBP30 | 27650-2 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: CREBBP (CBP) and EP300 are general transcriptional co-activators, which are involved in many biological...

Q-VD(OMe)-OPh | 27640-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Q-VD-OPh is a broad spectrum caspase inhibitor that provides a cost effective, non toxic, and highly speci?c means of...

CAY10625 | 27321 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis/Inhibitors & Activators Application: N/A Background: N/A Description: Caspase-3 and -7 Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

XL-888 | 27781-3 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: X-ray crystallographic analysis reveals that the XL-888 binds to HSP90 through the formation of H-bonding...

PYR-41 | 27716-3 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: Useful for inhibition of E1 ubiquitin conjugating enzymes Background: N/A Description: PYR-41 is a cell permeable, irreversible...

PR-619 | 27714-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for non-specific inhibition of ubiquitin-like isopeptidases for cell biology and drug discovery studies. Background: ...

PS-341 (MG-341) | 27715-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for as a potent, cell permeable proteasome inhibitor for drug discovery research. Background: N/A ...

PCI 34051 | 27316 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Caspase and HDAC Inhibitor Product Type: Inhibitor Shippement Condition: room temp or...

NU 7026 | 27312 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: N/A Description: PARP3 Inhibitor Product Type: Inhibitor Shippement Condition: gel packs

Milrinone | 27308 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: PDE Inhibitor Product Type: Inhibitor Shippement Condition: room temp or gel...

VX-765 | 27779-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VX-765 is an orally-absorbed pro-drug of VRT-043198, a potent and selective inhibitor of ICE/caspase-1 sub-family caspases...

NVP-BEP800 | 27766-3 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: NVP-BEP800 binds to the N-terminal ATP-binding pocket of Hsp90. Hsp90 is a ubiquitously expressed molecular...

SGI-1776 free base | 27651-3 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: According to preliminary results from studies treating prostate cancer cells, SGI-1776 dose-dependently reduces...

Posaconazole | 27639-2 | Gentaur US, UK & Europe Disrtribition Category: Demethylase/Inhibitors / Activators Application: N/A Background: Posaconazole, also known as SCH 56592 or Noxafil, is a novel triazole antifungal compound that potently...

OG-L002 | 27635-2 | Gentaur US, UK & Europe Disrtribition Category: Demethylase/Inhibitors / Activators Application: N/A Background: N/A Description: N/A Product Type: Inhibitor Shippement Condition: Room temp. (continental US) or gel...

Z-FA-FMK | 27667-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: N/A Product Type: Inhibitor Shippement Condition: Room temp. (continental US) or gel packs

Z-DQMD-FMK | 27666-3 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Z-DQMD-FMK is a potent cell-permeable inhibitor of caspase-3. Researchers have shown that expression of a short peptide of 15...

C646 | 27613-2 | Gentaur US, UK & Europe Disrtribition Category: Acetyltransferase/Inhibitors / Activators Application: N/A Background: C646 binds to p300 as the Z-isomer forming hydrogen bonds between Thr1411, tYR1467, Trp1466 and Arg1410 on...

PCI-24781 (CRA-024781) | 27769-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: PCI-24781 is a pan-HDAC inhibitor that shows antitumor activity in vitro and in vivo...

P22077 | 27712-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: Useful for inhibition of USP7 and USP47 activity. Background: N/A Description: P22077 is a cell permeable inhibitor of the...

Roflumilast | 27645-3 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: The enzyme PDE-4 is found mainly in inflammatory cells, and Roflumilast acts as a selective,...

JNJ-26481585 | 27632-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Quisinostat, also known asJNJ-26481585, is an orally bioavailable, second-generation, hydroxamic acid-based...

SB 939 | 27331 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

EPZ015666 | 79043-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: N/A Description: EPZ015666 is a potent, selective, competitive PRMT5 inhibitor (IC50 = 22 nM)...

Oxamflatin | 27326 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: Inhibitor Shippement Condition: room temp or gel packs

Z-VAD(OMe)-FMK | 27313 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: Z-VAD(OMe)-FMK is a cell permeable, irreversible pan-caspase inhibitor and anti-apoptotic agent. It has...

Vardenafil HCl Trihydrate | 27776-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Vardenafil is frequently used in the treatment erectile dysfunction, and is the active...

Rucaparib (AG-014699,PF-01367338) | 27647-3 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP)...

Belinostat (PXD101) | 27608-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Belinostat has been found to significantly increase the acetylation of histones H3 and H4 and exerts...

Embelin | 27322 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis/Inhibitors & Activators Application: N/A Background: N/A Description: XIAP Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

LDN-57444 | 27706-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for the inhibition of Ubiquitin C-terminal Hydrolase (UCH-L1) in drug discovery studies. Background: N/A ...

Celastrol | 27702-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of NF-κappa-B-dependent pathways and inhibition of 20S proteasome chymotrypsin-like activity. ...

Caspase-3/7 Inhibitor I | 27741-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Selectivity for caspases-3 and 7 involves unique hydrophobic residues in the S2 pocket surrounding the catalytic...

EPZ-6438 | 27626-3 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ-6438 competitively binds to the S-adenosylmethionine (SAM) binding site of EZH2 and also...

3-Deazaneplanocin A (DZNep) hydrochloride | 27618-1 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: 3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase...

3-Deazaneplanocin (DZNep) | 27617-1 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: 3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase inhibitor and histone...

GSK J4 HCl | 27627-2 | Gentaur US, UK & Europe Disrtribition Category: Demethylase/Inhibitors / Activators Application: N/A Background: GSK J4 is a potent cell-permeable inhibitor of the histone H3 lysine 27 (H3K27) demethylase JMJD3. GSK J4 is...

Z-FA-FMK | 27667-3 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: N/A Product Type: Inhibitor Shippement Condition: Room temp. (continental US) or gel packs

I-BET151 (GSK1210151A) | 27629-3 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific...

Apoptosis Inhibitor | 27734-3 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis induction. It does not directly...

OTX-015 | 27636-2 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites, including...

Trimidox | 27319 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis/Inhibitors & Activators Application: N/A Background: N/A Description: Caspase Activator Product Type: Inhibitor Shippement Condition: room temp.

IPI-504 (Retaspimycin hydrochloride) | 27753-1 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: Cancer cells depend on the Hsp90 chaperone to maintain many proteins critical for...

Telotristat | 27341 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: N/A Description: Telotristat is the active metabolite of LX1606 (Telotristat etiprate), which is an...

SIRT1/2 Inhibitor IV | 27323 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: SIRT1/2 Inhibitor IVCatalog #: 27323Size: 25 mgSIRT1 and 2 Inhibitor Product...

IWP-L6 | 27755-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: WP-L6 was developed as a sub-nanomolar inhibitor of Porcupine, the enzyme that catalyzes the palmitoylation of Wnt...

Tenovin-1 | 27660-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Tenovin-1, a small molecule discovered by a cell-based screen, is a bio-active activator of p53 that elevates...

S- (+)-Rolipram | 27648-3 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Rolipram is a racemic drug that increases brain cAMP availability by inhibiting phosphodiesterase...

ME0328 | 27634-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: N/A Description: ME0328 is a potent and selective PARP inhibitor with about 7-fold selectivity over PARP3 over PARP1...

ML161 | 27764-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: ML-161 is thought to act allosterically. ML-161 inhibits thrombin-induced platelet activation. Description: ...

Romidepsin (FK228, depsipeptide) | 27646-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Romidepsin is a bicyclic depsipeptide antibiotic isolated from the bacterium...

I-BET-762 | 27630-2 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites,...

BMN 673 | 27609-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: BMN673 has shown anti-tumor activity both in vitro and in vivo. It inhibited proliferation of tumor cells and...

b-AP15 (NSC-687852) | 27701-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Suitable for validation studies of the deubiquitinating activities of the 19S regulatory particle as a drug target,...

Z-VEID-FMK | 27669-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VEID is the specific recognition sequence for caspase-6/Mch2. Caspase 6 is only one of at least three effector caspases, the...

Z-VDVAD-FMK | 27668-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VDVAD has been shown to be a preferred cleavage site for caspase-2. Caspase 2 is a very versatile caspase with multiple...

Q-VD(OMe)-OPh | 27640-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Q-VD-OPh is a broad spectrum caspase inhibitor that provides a cost effective, non toxic, and highly speci?c means of...

JW 55 | 27633-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased...

Apicidin | 27329 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC3 &HDAC6 Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

Pyroxamide | 27328 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: Inhibitor Shippement Condition: gel packs

SMI-4a | 27774-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: The serine/threonine Pim kinases have been suggested to promote the activity of the rapamycin-sensitive mammalian target of...

UPF 1069 | 27665-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: N/A Description: UPF 1069, a derivative of isoquinolinone, is a potent and selective inhibitor of poly-(ADP-ribose)...

VER 155008 | 27777-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: VER 155008 is a potent inhibitor of heat shock protein 70 (Hsp70) family of chaperones, which have been...

Rocilinostat (ACY-1215) | 27644-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Rocilinostat, also known as ACY-1215, is a selective HDAC6 inhibitor with...

AG-14361 | 27602-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: A 17-hour exposure of A549 cells to 0.4 µM AG14361 does not change the expression of the 6800 genes. Thus, although 0...

ND-630 | 27071-2 | Gentaur US, UK & Europe Disrtribition Category: Metabolic Enzymes/Inhibitors Application: N/A Background: N/A Description: ND-630 (NDI 010976) is a highly specific, reversible inhibitor of ACC1 (IC50 = 2 nM) and ACC2 (IC50...

Lactacystin | 27705 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of the 20S proteasome. Background: N/A Description: Lactacystin is a cell-permeable, potent and...