Description
Inhibin alpha Antibody / INHA | F54878-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, FACS, IHC-P, IF
Buffer: N/A
Limitation: This Inhibin alpha antibody is available for research use only.
Purity: Antigen affinity purified
Description: The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
Immunogen: A portion of amino acids 79-108 from the human protein was used as the immunogen for the Inhibin alpha antibody.
Storage: Aliquot the Inhibin alpha antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
