Description
Influenza A [Wisconsin/588/2019 (H1N1) ] Neuraminidase (NA) Protein, His Tag | NEE-V524k-1mg| Gentaur Distribution US, UK & Europe
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
Source: Influenza A [Wisconsin/588/2019 (H1N1) ] Neuraminidase (NA) Protein, His Tag (NEE-V524k) is expressed from human 293 cells (HEK293). It contains AA Val 80 - Lys 469 (Accession # EPI_ISL_404527, GISAID).
Format: Liquid.
Tag: N-10×His.
Expression System: HEK293.
Expression Region: Val 80 - Lys 469.
Conjugate: Unconjugated.
Molecular Weight: 50.8 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 50.8 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 50 mM Tris, 300 mM NaCl, 2 mM TCEP, pH 7.5.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice