Description
Influenza A [Sydney/5/2021] Neuraminidase (NA) Protein, His Tag (SPR verified) | NEE-V5248-1mg| Gentaur Distribution US, UK & Europe
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
Source: Influenza A [Sydney/5/2021] Neuraminidase (NA) Protein, His Tag (NEE-V5248) is expressed from human 293 cells (HEK293). It contains AA Ser 35 - Lys 469 (Accession # EPI_ISL_8767089, GISAID).
Format: Powder.
Tag: N-10×His.
Expression System: HEK293.
Expression Region: Ser 35 - Lys 469.
Conjugate: Unconjugated.
Molecular Weight: 55.9 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 55.9 kDa. The protein migrates as 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT