Description
IL1B Polyclonal Antibody | E-AB-52116 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB, ELISA
Research Area: Cancer, Cardiovascular, Metabolism, Immunology
Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Lead Time: 7~10 days
Concentration: 0.7 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human IL1B
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: 31 kDa
Observed Molecular Weight: Refer to figures
Clonality: Polyclonal
