IL-23: IL-23R[Biotinylated] Inhibitor Screening ELISA Kit | EP-167-96tests

IL-23: IL-23R[Biotinylated] Inhibitor Screening ELISA Kit | EP-167| Gentaur Distribution US, UK & Europe

Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Source: Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Molecule: ILN/A23.

Format: Solid.

Species: Human.

Application: This kit is developed for screening for inhibitors of human IL-23 binding to human IL-23R.

Kit Component: N/A.

Stability: The unopened kit should be stored at 2°C to 8°C. The shelf life is 12 months from the date of receipt. The opened kit should be stored at 2°C to 8°C. The shelf life is 1 month from the date of opening.

Storage Conditions: 2-8℃.

Shipping Conditions: RT